Gloria Zaffaroni, Miguel Cunha and Gabriela Möslein

On 3 Jul 2020

A paper and visual abstract on microsatellite instability by Gloria Zaffaroni, Miguel Cunha and Gabriela Möslein.

Zoe Garoufalia, Gloria Zaffaroni and Toni Seppälä

On 25 Jun 2020

Interview by Zoe Garoufalia and Gloria Zaffaroni. Lynch syndrome is characterised by predisposition to colorectal, endometrial, and other cancers, and is caused by autosomal dominant inherited pathogenic variants affecting the DNA mismatch repair (MMR) genes MLH1, MSH2, MSH6, and PMS2. It is probably the most common predisposition to cancer. Despite its high estimated prevalence, up until now, there were no reliable long term data of MMR variant carriers in order to plan their treatment according to evidence-based medicine principles.

#ColorectalLive with Prof. Gabriela Möslein, 22 June, 7pm BST

On 18 Jun 2020

The anticipated next instalment in the series of Johnson & Johnson Institute’s #ColorectalLive interviews will be broadcast live on Twitter this Monday 22nd June at 19.00 BST. The #ColorectalLive series is being re-launched with an exciting line-up of interviews after being postponed in March following the outbreak of the global COVID-19 pandemic.

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On 17 Jun 2020

ESCP's Research Committee invites applications for their new role, Y-ESCP Communications Representative.

Danilo Miskovic and Roel Hompes

On 12 Jun 2020

Interview by Zoe Garoufalia. Transanal Total Mesorectal Excision (TaTME) is a relatively recent surgical procedure that was originally pioneered to overcome difficulties in addressing rectal cancer and especially low rectal cancer via a pure abdominal approach. It is quite a controversial technique, because despite initial data [1] showing non-inferiority to laparoscopic or open TME, a recent Norwegian report raised concern due to high rates of multifocal pelvic recurrences [2]. Nevertheless it is unclear whether these issues are related to the technique itself or to poor adherence to recommendations and insufficient training. Therefore, an international panel of expert surgeons supported by 14 international surgical societies was appointed to provide an up-to-date consensus on the safe implementation and application of TaTME.

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