COLD: Study of Oncological Outcomes of D3 Lymph Node Dissection in Colon Cancer

Trial Overview

Acronym	COLD
Number	NCT03009227
Protocol Link	https://www.dropbox.com/s/znqwxo2ygwk6kct/Protocol_COLD_1.1_eng.pdf?dl=0
Public Trial Registry Link	https://clinicaltrials.gov/ct2/show/NCT03009227
Status	Open/recruiting
Category	Colorectal Cancer - Colonic Specific
Treatment Course	Surgery

Trial Description

The design involves random allocation of eligible patients undergoing colonic resection to D3 or D2 lymph node dissection group in 1:1 ratio. A 3 year accrual period and 5 year follow up is planned. The intent-to-treat principle is used for the data analysis. Primary endpoint is overall survival

Chief Investigator

Aleksei Karachun Professor

Profile Link

Lead Centre

National Medical Research Center named after N.N. Petrov ul. Leningradskaya, house 68 St Petersburg 197758 Russia

Website

Collaborative Sites

1. National Medical Research Center of Oncology named after N.N. Petrov 68 Leningradskaya street Saint-Petersburg 197758 Russia Contact: Aleksei Karachun

2. State Scientific Centre of Coloproctology Ulitsa Salyama Adilya, 2 Moscow 123423 Russia Contact: Segei Achkasov

3. Saint-Petersburg Clinical Research center of specialized kinds of medical care (Oncology) 68A Leningradskaya street Saint-Petersburg 197758 Russia Contact: Ilya Chernikovskiy

4. Rostov Research Institute of Oncology Ulitsa 14 Liniya, 63 Rostov 344037 Russia Contact: Yuriy Gevorkyan

5. P. Herzen Moscow Oncology Research Institute 2-Y Botkinskiy Proyezd, 3 Moscow 125284 Russia Contact: Dmitrii Sidorov